Question · asked by 1 review

Fingolimod 0.5 mg vs interferon beta‐1a: Participants free from disability worsening

Fingolimod 0.5 mg showed no clear difference in participants free from disability worsening compared with interferon beta‐1a (low certainty).

What each review found

Include earlier review versions
FindingEffectStudiesGRADE certainty
Fingolimod 0.5 mg vs interferon beta‐1a
Participants free from disability worsening · people with relapsing‐remitting multiple sclerosis
Fingolimod 0.5 mg showed no clear difference in participants free from disability worsening compared with interferon beta‐1a (low certainty).
Fingolimod for relapsing‐remitting multiple sclerosis (2016) · Cochrane Headline outcomes only
RR 1.02 [0.99, 1.06]1 study · 860 participantsLow

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Fingolimod for relapsing‐remitting multiple sclerosis
2016 · Cochrane Headline outcomes only
Not reportedlist not extracted yetNot assessed

Studies behind the findings

None of these reviews ties its included studies to this outcome in the data here. Cochrane reviews and reviews with headline outcomes only do not list their studies yet.

How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.