Question · asked by 1 review

Oral retinoids: alitretinoin 30 mg vs placebo: Primary: participant‐rated good/excellent control of symptoms

Oral retinoids: alitretinoin 30 mg leads to higher primary: participant‐rated good/excellent control of symptoms… compared with placebo (high certainty).

What each review found

Include earlier review versions
FindingEffectStudiesGRADE certainty
Oral retinoids: alitretinoin 30 mg vs placebo
Primary: participant‐rated good/excellent control of symptoms Folluw‐up: 48 weeks to 72 weeks · people with moderate to severe chronic hand eczema
Oral retinoids: alitretinoin 30 mg leads to higher primary: participant‐rated good/excellent control of symptoms… compared with placebo (high certainty).
Interventions for hand eczema (2019) · Cochrane Headline outcomes only
RR 2.75 [2.18, 3.48]2 studies · 1210 participantsHigh

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Interventions for hand eczema
2019 · Cochrane Headline outcomes only
Not reportedlist not extracted yetNot assessed

Studies behind the findings

None of these reviews ties its included studies to this outcome in the data here. Cochrane reviews and reviews with headline outcomes only do not list their studies yet.

How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.