Mouth-rinse probiotic vs placebo or control: Salivary pH
In a subgroup analysis, mouth-rinse probiotics reduced salivary pH (MD -0.40, 95%CI -0.54 to -0.26; p-interaction<0.01); not GRADE-rated.
What each review found
Include earlier review versions| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
Mouth-rinse probiotic vs No treatment or placebo (control) Salivary pH · Children and/or adolescents (<18 years) without background systemic disease · Healthy children and/or adolescents (<18 years) without systemic disease; RCTs from multiple countries (India, Thailand, Spain, Australia, New Zealand, Sweden, Poland, Colombia, Saudi Arabia); mostly school/community and clinic settings, Probiotic presentation: mouth rinse (vs other presentations; p-interaction<0.01) In a subgroup analysis, mouth-rinse probiotics reduced salivary pH (MD -0.40, 95%CI -0.54 to -0.26; p-interaction<0.01); not GRADE-rated. Efficacy of Probiotic Consumption on Oral Outcomes in Children and/or Adolescents: A Meta-Analysis. (2024) All outcomes | MD -0.40 [-0.54, -0.26] | Not reported | GRADE not reported |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Efficacy of Probiotic Consumption on Oral Outcomes in Children and/or Adolescents: A Meta-Analysis. 2024 All outcomes | March 15, 2023 | 19 | Critically Low / Critically Low |
Studies behind the findings
None of these reviews ties its included studies to this outcome in the data here. Cochrane reviews and reviews with headline outcomes only do not list their studies yet.
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.