NSAIDs vs placebo: Participant‐reported pain relief of 50% or greater
- Population
- acute gout
- Intervention
- NSAIDs
- Comparison
- placebo
- Outcome
- Participant‐reported pain relief of 50% or greater
NSAIDs may leads to higher pain: ≥ 50% improvement in pain (spontaneous pain at 24 hours) compared with placebo (low certainty).
What each review found
Include earlier review versions| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
NSAIDs vs placebo Pain: ≥ 50% improvement in pain (spontaneous pain at 24 hours) · acute gout NSAIDs may leads to higher pain: ≥ 50% improvement in pain (spontaneous pain at 24 hours) compared with placebo (low certainty). Non‐steroidal anti‐inflammatory drugs for acute gout (2021) · Cochrane Headline outcomes only | RR 2.75 [1.13, 6.72] | Not reported | Low |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Non‐steroidal anti‐inflammatory drugs for acute gout 2021 · Cochrane Headline outcomes only | Not reported | Not extracted | Not assessed |
Related questions
The same intervention and outcome, asked in another population or against another comparator.
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How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.