Question · asked by 1 review

Metoprolol vs placebo or no treatment: Withdrawals due to adverse events

Metoprolol leads to higher withdrawals due to adverse effects compared with placebo or no treatment (high certainty).

What each review found

Include earlier review versions
FindingEffectStudiesGRADE certainty
Metoprolol vs placebo or no treatment
Withdrawals due to adverse effects · adults in sinus rhythm after cardioversion of atrial fibrillation
Metoprolol leads to higher withdrawals due to adverse effects compared with placebo or no treatment (high certainty).
Antiarrhythmics for maintaining sinus rhythm after cardioversion of atrial fibrillation (2019) · Cochrane Headline outcomes only
RR 3.47 [1.48, 8.1]2 studies · 562 participantsHigh

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Antiarrhythmics for maintaining sinus rhythm after cardioversion of atrial fibrillation
2019 · Cochrane Headline outcomes only
Not reportedlist not extracted yetNot assessed

Studies behind the findings

None of these reviews ties its included studies to this outcome in the data here. Cochrane reviews and reviews with headline outcomes only do not list their studies yet.

How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.