Question · asked by 1 review

Summary of findings table ‐ Continuation vs reduction of polypharmacy: Leaving the study early ‐ for any reason ‐ overall acceptability (combined time points)

Summary of findings table ‐ Continuation may leads to lower leaving the study early due to any reason – overall acceptability… compared with reduction of polypharmacy (low certainty).

What each review found

Include earlier review versions
FindingEffectStudiesGRADE certainty
Summary of findings table ‐ Continuation vs reduction of polypharmacy
Leaving the study early due to any reason – overall acceptability (totals of time points combined) · people with schizophrenia
Summary of findings table ‐ Continuation may leads to lower leaving the study early due to any reason – overall acceptability… compared with reduction of polypharmacy (low certainty).
Antipsychotic polypharmacy reduction versus polypharmacy continuation for people with schizophrenia (2022) · Cochrane Headline outcomes only
RR 0.44 [0.29, 0.68]5 studies · 319 participantsLow

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Antipsychotic polypharmacy reduction versus polypharmacy continuation for people with schizophrenia
2022 · Cochrane Headline outcomes only
Not reportedlist not extracted yetNot assessed

Studies behind the findings

None of these reviews ties its included studies to this outcome in the data here. Cochrane reviews and reviews with headline outcomes only do not list their studies yet.

How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.