Question · asked by 1 review

Late paracetamol vs placebo or no intervention: Necrotizing enterocolitis during initial hospital stay (by radiological diagnosis)

Late paracetamol showed no clear difference in necrotizing enterocolitis during initial hospital stay (by… compared with placebo/no intervention (low certainty).

What each review found

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FindingEffectStudiesGRADE certainty
Late paracetamol vs placebo/no intervention
Necrotizing enterocolitis during initial hospital stay (by radiological diagnosis) · preterm or low birth weight infants with PDA
Late paracetamol showed no clear difference in necrotizing enterocolitis during initial hospital stay (by… compared with placebo/no intervention (low certainty).
Paracetamol (acetaminophen) for patent ductus arteriosus in preterm or low birth weight infants (2022) · Cochrane Headline outcomes only
RR 1.04 [0.07, 15.76]1 study · 55 participantsLow

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Paracetamol (acetaminophen) for patent ductus arteriosus in preterm or low birth weight infants
2022 · Cochrane Headline outcomes only
Not reportedlist not extracted yetNot assessed

Studies behind the findings

None of these reviews ties its included studies to this outcome in the data here. Cochrane reviews and reviews with headline outcomes only do not list their studies yet.

How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.