Procalcitonin algorithm vs usual care: Adverse effects of antibiotics
Procalcitonin algorithm probably leads to lower antibiotic‐related side effects compared with standard care (moderate certainty).
What each review found
Include earlier review versions| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
Procalcitonin algorithm vs standard care Antibiotic‐related side effects · people with acute respiratory tract infections Procalcitonin algorithm probably leads to lower antibiotic‐related side effects compared with standard care (moderate certainty). Procalcitonin to initiate or discontinue antibiotics in acute respiratory tract infections (2017) · Cochrane Headline outcomes only | OR 0.68 [0.57, 0.82] | 6 studies · 3034 participants | Moderate |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Procalcitonin to initiate or discontinue antibiotics in acute respiratory tract infections 2017 · Cochrane Headline outcomes only | Not reported | list not extracted yet | Not assessed |
Studies behind the findings
None of these reviews ties its included studies to this outcome in the data here. Cochrane reviews and reviews with headline outcomes only do not list their studies yet.
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.