Same question across reviews · CL0304
other :: Pit-and-fissure sealants -> Restoration survival/failure
ProposalThis cluster groups questions by review type, intervention category and outcome domain. It is a proposal pending human validation, so questions in it may differ in population, comparator or timing.
Reviews
1
Questions
6
current versions
GRADE rated
0
Review overlap (CCA)
NR
over all included studies of these reviews, not this question only
| Question | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Resin-based fissure sealants vs Glass-ionomer cement-based fissure sealants Retention-to-caries risk ratio (RCR) · Patients with fissure-sealed permanent molar teeth · Longest follow-up per trial, Sensitivity analysis Validity of sealant retention as surrogate for caries prevention--a systematic review. (2013) | Mean RCR (retention-to-caries risk ratio); t-test of difference Resin vs GIC difference not statistically significant (p=0.069); sensitivity-analysis mean RCRs not reported | 14 studies | Ungraded |
Glass-ionomer cement-based fissure sealants vs No comparator (within-material surrogate-validity regression) Association between loss of complete retention risk and caries occurrence risk · Patients with fissure-sealed permanent molar teeth · At least 24 months, Main analysis Validity of sealant retention as surrogate for caries prevention--a systematic review. (2013) | Regression slope (ln caries risk on ln retention-loss risk) 0.81 [-0.07, 1.68] | 22 studies · 3768 participants | Ungraded |
Resin-based fissure sealants vs No comparator (within-material surrogate-validity regression) Association between loss of complete retention risk and caries occurrence risk · Patients with fissure-sealed permanent molar teeth · At least 24 months, Main analysis Validity of sealant retention as surrogate for caries prevention--a systematic review. (2013) | Regression slope (ln caries risk on ln retention-loss risk) 0.89 [0.56, 1.23] | 54 studies · 17377 participants | Ungraded |
Glass-ionomer cement-based fissure sealants vs No comparator (within-material surrogate-validity regression) Association between loss of complete retention risk and caries occurrence risk · Patients with fissure-sealed permanent molar teeth · Longest follow-up per trial, Sensitivity analysis Validity of sealant retention as surrogate for caries prevention--a systematic review. (2013) | Regression slope (ln caries risk on ln retention-loss risk) 1.44 [0.71, 2.18] | 14 studies · 2307 participants | Ungraded |
Resin-based fissure sealants vs Glass-ionomer cement-based fissure sealants Retention-to-caries risk ratio (RCR) · Patients with fissure-sealed permanent molar teeth · At least 24 months, Main analysis Validity of sealant retention as surrogate for caries prevention--a systematic review. (2013) | Mean RCR (retention-to-caries risk ratio); t-test of difference Resin mean RCR 9.64 (SD 24.58) vs GIC 13.68 (SD 13.72); p=0.017 | 62 studies | Ungraded |
Resin-based fissure sealants vs No comparator (within-material surrogate-validity regression) Association between loss of complete retention risk and caries occurrence risk · Patients with fissure-sealed permanent molar teeth · Longest follow-up per trial, Sensitivity analysis Validity of sealant retention as surrogate for caries prevention--a systematic review. (2013) | Regression slope (ln caries risk on ln retention-loss risk) 0.53 [-0.27, 1.32] | 14 studies · 3154 participants | Ungraded |