Same question across reviews · CL0232

intervention :: Pit-and-fissure sealants -> Caries increment (DMFS/DMFT)

ProposalThis cluster groups questions by review type, intervention category and outcome domain. It is a proposal pending human validation, so questions in it may differ in population, comparator or timing.
Reviews
3
Questions
5
current versions
GRADE rated
0
Review overlap (CCA)
NR
over all included studies of these reviews, not this question only
QuestionEffectEvidenceStatus / GRADE
Resin-based pit and fissure sealant (PFS) vs Fluoride varnish (FV)
DMFS (decayed, missing, filled surfaces) increment, occlusal surfaces · Schoolchildren aged 6-12 years with sound occlusal surfaces of the first permanent molars · 24 months
Pit and Fissure Sealant versus Fluoride Varnish for the Prevention of Dental Caries in School Children: A… (2022)
MD 0.09 [-0.03, 0.21]2 studies · 762 participantsUngraded
Fluoride-releasing resin-based sealant vs No sealant (no treatment)
Mean caries increment (mean number of new cavitated occlusal lesions) · Children with caries-free or non-cavitated carious lesion primary molars, aged 3-7 years (paediatric department,… · 24 months
Sealants for preventing dental caries in primary teeth (2022) · Cochrane
Mean number of new cavitated occlusal lesions 0.23 (SD 0.06) in sealed molars vs 0.29 (SD 0.06) in control molars (Wilcoxon matched-pairs signed-rank test P = 0.42)1 study · 85 participantsUngraded
Glass ionomer-based sealant vs No sealant
Mean caries increment (dmft) · Children with caries-free primary first molars (with or without caries on other teeth), aged 1-5 years (paediatric… · 12 months
Sealants for preventing dental caries in primary teeth (2022) · Cochrane
Joshi 2019: dmft 8.43 (SD 5.84) with sealant vs 10.05 (SD 6.16) with no sealant at 12 months (caries threshold uncertain); Chadwick 2005: no significant difference in caries increment on occlusal surfaces, no summary…2 studiesUngraded
Resin-based fissure sealant vs Fluoride varnish
Change in DMFT (decayed, missing and filled permanent teeth) increment · Children and adolescents from the general population, younger than 20 years of age at the start of the study · 2 years
Pit and fissure sealants versus fluoride varnishes for preventing dental decay in the permanent teeth of… (2020) · Cochrane
MD -0.08 [-0.14, -0.02]1 study · 542 participantsUngraded
Resin-based fissure sealant vs Fluoride varnish
Change in DMFS (decayed, missing and filled permanent surfaces) increment · Children and adolescents from the general population, younger than 20 years of age at the start of the study · 2 years
Pit and fissure sealants versus fluoride varnishes for preventing dental decay in the permanent teeth of… (2020) · Cochrane
MD -0.09 [-0.15, -0.03]1 study · 542 participantsUngraded

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