Same question across reviews · CL0231
intervention :: Pit-and-fissure sealants -> Caries incidence/onset
ProposalThis cluster groups questions by review type, intervention category and outcome domain. It is a proposal pending human validation, so questions in it may differ in population, comparator or timing.
Reviews
2
Questions
8
current versions
GRADE rated
7
Review overlap (CCA)
NR
over all included studies of these reviews, not this question only
| Question | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Fluoride-releasing resin-based sealant vs No sealant (no treatment) Development of >=1 new carious lesion (caries incidence) · Children with caries-free or non-cavitated carious lesion primary molars, aged 3-7 years (paediatric department,… · 12 months Sealants for preventing dental caries in primary teeth (2022) · Cochrane | BB OR 1.21 [0.37, 3.94] | 1 study · 88 participants | Low |
Glass ionomer-based sealant vs No sealant Development of >=1 new carious lesion (caries incidence) · Children with caries-free primary first molars (with or without caries on other teeth), aged 1-5 years (paediatric… · 6-12 months Sealants for preventing dental caries in primary teeth (2022) · Cochrane | OR 0.033 [0.007, 0.149] | 1 study · 107 participants | Low |
Glass ionomer-based sealant vs No sealant Development of >=1 new carious lesion (caries incidence) · Children with caries-free primary first molars (with or without caries on other teeth), aged 1-5 years (paediatric… · 12-30 months Sealants for preventing dental caries in primary teeth (2022) · Cochrane | OR 0.97 [0.63, 1.49] | 1 study · 449 participants | Low |
Glass ionomer-based sealant vs Resin-based sealant (fluoride-releasing or non-fluoride-releasing) Development of >=1 new carious lesion (caries incidence) · 'Healthy' children with caries-free second primary molars, aged 3-5 years (schools and kindergartens, India and China) · 6-24 months Sealants for preventing dental caries in primary teeth (2022) · Cochrane | N/A - insufficient quantitative information available; 200 (2 studies). Comments: Due to the methods of data collection, analysis and reporting we were unable to provide any quantitative estimates. Fei 2011 narrative:… | 2 studies · 200 participants | Very low |
Fluoride-releasing resin-based sealant vs Resin-based sealant Development of >=1 new carious lesion (caries incidence) · Children with caries-free second primary molars, aged 4-8 years (dental clinic, Turkey and Spain) · 6-24 months Sealants for preventing dental caries in primary teeth (2022) · Cochrane | N/A - insufficient quantitative information available; 69 (2 studies). Comments: Due to the different sealant materials, data reporting (split-mouth studies reported as parallel-group) and the very low number of tooth… | 2 studies · 69 participants | Low |
Autopolymerised sealant vs Light polymerised sealant Development of >=1 new carious lesion (caries incidence) · Children with sound primary molars, aged 2-4 years (municipal dental clinics or hospital paediatric clinics, Denmark) · 24-36 months Sealants for preventing dental caries in primary teeth (2022) · Cochrane | OR 0.58 [0.15, 2.19] | 1 study · 52 participants | Very low |
Fluoride-releasing resin-based sealant vs No sealant (no treatment) Development of >=1 new carious lesion (caries incidence) · Children with caries-free or non-cavitated carious lesion primary molars, aged 3-7 years (paediatric department,… · 24 months Sealants for preventing dental caries in primary teeth (2022) · Cochrane | BB OR 0.76 [0.41, 1.42] | 1 study · 85 participants | Low |
Resin-based pit and fissure sealant (PFS) vs Fluoride varnish (FV) Caries incidence in first permanent molars · Schoolchildren aged 6-12 years with sound occlusal surfaces of the first permanent molars · 24 months Pit and Fissure Sealant versus Fluoride Varnish for the Prevention of Dental Caries in School Children: A… (2022) | RR 0.65 [0.31, 1.38] | 3 studies · 1263 participants | Ungraded |