Same question across reviews · CL0222

intervention :: Oral hygiene/education -> Periodontal/gingival

ProposalThis cluster groups questions by review type, intervention category and outcome domain. It is a proposal pending human validation, so questions in it may differ in population, comparator or timing.
Reviews
9
Questions
41
current versions
GRADE rated
36
Review overlap (CCA)
0.047
over all included studies of these reviews, not this question only
QuestionEffectEvidenceStatus / GRADE
Theory-based oral health education/promotion interventions (HBM, TPB, SCT, HAPA, TTM, PMT, SOC, PRECEDE-PROCEED, MI) vs Control (waitlist, routine/standard oral health education, or minimal intervention)
Periodontal health (gingival/periodontal indices) · Children and adolescents aged 5-18 years · Post-intervention (follow-up 2 weeks to 6 months, varies by study), Overall
Health promotion theory-based educational interventions for improving oral health in children and… (2025)
SMD -1.18 [-1.83, -0.53]4 studies · 3342 participantsModerate
Primary school-based interventions (one or more of: school health policy, oral health education, healthy school environment, access to oral health services, community involvement) vs No intervention or usual practice/activities
Oral hygiene measured by mean gingival scores · Primary school children (aged 3-16 years) attending primary school in low- and middle-income countries (LMICs) · Post-intervention; follow-up varied across studies (interventions ranged from <2 years to >=2 years and longer)
Effectiveness of primary school-based interventions in improving oral health of children in low- and… (2022)
SMD 0.12 [-0.32, 0.55]3 studies · 1573 participantsVery low
Rubber/elastomeric cleaning stick plus toothbrushing vs Toothbrushing alone
Gingivitis (proportion of bleeding sites) · Adults, 16 years and older (dentate) · 1 month
Home use of interdental cleaning devices, in addition to toothbrushing, for preventing and controlling… (2019) · Cochrane
MD -0.07 [-0.15, 0.01]1 study · 30 participantsVery low
Rubber/elastomeric cleaning stick plus toothbrushing vs Flossing plus toothbrushing
Gingivitis (gingival index) · Adults, 16 years and older (dentate) · 4 to 6 weeks
Home use of interdental cleaning devices, in addition to toothbrushing, for preventing and controlling… (2019) · Cochrane
SMD -0.22 [-0.69, 0.24]6 studies · 256 participantsVery low
Wooden cleaning stick plus toothbrushing vs Toothbrushing alone
Gingivitis (gingival index) · Adults, 16 years and older (dentate)
Home use of interdental cleaning devices, in addition to toothbrushing, for preventing and controlling… (2019) · Cochrane
Gingivitis measured by gingival index: Not measured.0 studiesNo studies
Interdental brushing plus toothbrushing vs Toothbrushing alone
Gingivitis (gingival index) · Adults, 16 years and older (dentate) · 1 month
Home use of interdental cleaning devices, in addition to toothbrushing, for preventing and controlling… (2019) · Cochrane
MD -0.53 [-0.83, -0.23]1 study · 62 participantsVery low
Oral irrigation plus toothbrushing vs Flossing plus toothbrushing
Gingivitis (gingival index) · Adults, 16 years and older (dentate) · 1 month
Home use of interdental cleaning devices, in addition to toothbrushing, for preventing and controlling… (2019) · Cochrane
MD -0.06 [-0.12, 0.00]1 study · 63 participantsVery low
Wooden cleaning stick plus toothbrushing vs Toothbrushing alone
Gingivitis (proportion of bleeding sites) · Adults, 16 years and older (dentate) · 3 months
Home use of interdental cleaning devices, in addition to toothbrushing, for preventing and controlling… (2019) · Cochrane
MD -0.25 [-0.37, -0.13]1 study · 24 participantsVery low
Electric toothbrush (self, carer or carer-assisted brushing) vs Manual toothbrush (self, carer or carer-assisted brushing)
Gingival inflammation (short term) · Children and adults with mixed levels of ID; setting home, residential, day care, school, mixed or not specified · Short term (<6 weeks)
Oral hygiene interventions for people with intellectual disabilities (2019) · Cochrane
Electric vs manual toothbrush. Assorted gingival indices scale 0-4, 2-4 weeks; 252 participants (4 RCTs); Low. Four studies showed no significant differences for gingival inflammation short term; data could not be…4 studies · 252 participantsLow
Oral irrigation plus toothbrushing vs Toothbrushing alone
Gingivitis (gingival index) · Adults, 16 years and older (dentate) · 1 month
Home use of interdental cleaning devices, in addition to toothbrushing, for preventing and controlling… (2019) · Cochrane
SMD -0.48 [-0.89, -0.06]4 studies · 380 participantsVery low
Interdental brushing plus toothbrushing vs Flossing plus toothbrushing
Gingivitis (proportion of bleeding sites) · Adults, 16 years and older (dentate) · 4 to 6 weeks
Home use of interdental cleaning devices, in addition to toothbrushing, for preventing and controlling… (2019) · Cochrane
MD -0.06 [-0.08, -0.03]6 studies · 234 participantsLow
Flossing plus toothbrushing vs Toothbrushing alone
Gingivitis (proportion of bleeding sites) · Adults, 16 years and older (dentate) · 1 month
Home use of interdental cleaning devices, in addition to toothbrushing, for preventing and controlling… (2019) · Cochrane
MD -0.03 [-0.14, 0.08]2 studies · 158 participantsVery low
Scheduled dental recall intervals (1-, 3- or 6-monthly; oral hygiene instruction with or without scale and polish) plus daily supervised toothbrushing by carers vs Usual care (no specific treatment)
Gingival pocketing (long term) · Adults (mean age 30.9 years), level of ID unclear; setting day centre · Long term (>12 months)
Oral hygiene interventions for people with intellectual disabilities (2019) · Cochrane
MD -0.60 [-0.97, -0.23]1 study · 304 participantsLow
Interdental brushing plus toothbrushing vs Flossing plus toothbrushing
Gingivitis (gingival index) · Adults, 16 years and older (dentate) · 4 to 6 weeks
Home use of interdental cleaning devices, in addition to toothbrushing, for preventing and controlling… (2019) · Cochrane
SMD -0.40 [-0.70, -0.11]3 studies · 183 participantsLow
Rubber/elastomeric cleaning stick plus toothbrushing vs Interdental brushing plus toothbrushing
Gingivitis (proportion of bleeding sites) · Adults, 16 years and older (dentate) · 1 month
Home use of interdental cleaning devices, in addition to toothbrushing, for preventing and controlling… (2019) · Cochrane
MD -0.02 [-0.10, 0.06]1 study · 31 participantsVery low
Flossing plus toothbrushing vs Toothbrushing alone
Gingivitis (gingival index) · Adults, 16 years and older (dentate) · 1 month
Home use of interdental cleaning devices, in addition to toothbrushing, for preventing and controlling… (2019) · Cochrane
SMD -0.58 [-1.12, -0.04]8 studies · 585 participantsLow
Oral irrigation plus toothbrushing vs Toothbrushing alone
Gingivitis (proportion of bleeding sites) · Adults, 16 years and older (dentate) · 1 month
Home use of interdental cleaning devices, in addition to toothbrushing, for preventing and controlling… (2019) · Cochrane
MD -0.00 [-0.07, 0.06]2 studies · 126 participantsLow
Oral irrigation plus toothbrushing vs Flossing plus toothbrushing
Gingivitis (proportion of bleeding sites) · Adults, 16 years and older (dentate) · 1 month
Home use of interdental cleaning devices, in addition to toothbrushing, for preventing and controlling… (2019) · Cochrane
MD -0.12 [-0.19, -0.05]2 studies · 133 participantsLow
Rubber/elastomeric cleaning stick plus toothbrushing vs Interdental brushing plus toothbrushing
Gingivitis (gingival index) · Adults, 16 years and older (dentate) · 4 to 6 weeks
Home use of interdental cleaning devices, in addition to toothbrushing, for preventing and controlling… (2019) · Cochrane
MD 0.10 [-0.32, 0.52]1 study · 61 participantsVery low
Electric toothbrush (self, carer or carer-assisted brushing) vs Manual toothbrush (self, carer or carer-assisted brushing)
Gingival inflammation (medium term) · Children and adults with mixed levels of ID; setting home, residential, day care, school, mixed or not specified · Medium term (6 weeks to 12 months)
Oral hygiene interventions for people with intellectual disabilities (2019) · Cochrane
MD 0.02 [-0.06, 0.09]2 studies · 120 participantsModerate
Scheduled dental recall intervals (1-, 3- or 6-monthly; oral hygiene instruction with or without scale and polish) plus daily supervised toothbrushing by carers vs Usual care (no specific treatment)
Gingival bleeding (long term) · Adults (mean age 30.9 years), level of ID unclear; setting day centre · Long term (>12 months)
Oral hygiene interventions for people with intellectual disabilities (2019) · Cochrane
MD -0.20 [-0.86, 0.46]1 study · 304 participantsLow
Wooden cleaning stick plus toothbrushing vs Flossing plus toothbrushing
Gingivitis (gingival index) · Adults, 16 years and older (dentate)
Home use of interdental cleaning devices, in addition to toothbrushing, for preventing and controlling… (2019) · Cochrane
Gingivitis measured by gingival index: Not measured.0 studiesNo studies
Interdental brushing plus toothbrushing vs Toothbrushing alone
Gingivitis (proportion of bleeding sites) · Adults, 16 years and older (dentate) · 1 month
Home use of interdental cleaning devices, in addition to toothbrushing, for preventing and controlling… (2019) · Cochrane
MD -0.05 [-0.13, 0.03]1 study · 31 participantsVery low
Special manual toothbrush (self, carer or carer-assisted brushing) vs Conventional manual toothbrush (self, carer or carer-assisted brushing)
Gingival inflammation (short term) · Children and adults with mixed levels of ID; setting home, residential, day care, school, mixed or not specified · Short term (<6 weeks)
Oral hygiene interventions for people with intellectual disabilities (2019) · Cochrane
MD -0.10 [-0.77, 0.57]1 study · 25 participantsLow
Oral hygiene training (toothbrushing routine) of people with ID vs No oral hygiene training of people with ID
Gingival inflammation (short term) · Children and adults with mild to profound ID; setting residential or school · Short term (<6 weeks)
Oral hygiene interventions for people with intellectual disabilities (2019) · Cochrane
MD -0.28 [-0.90, 0.34]1 study · 10 participantsVery low
Rubber/elastomeric cleaning stick plus toothbrushing vs Toothbrushing alone
Gingivitis (gingival index) · Adults, 16 years and older (dentate) · 1 month
Home use of interdental cleaning devices, in addition to toothbrushing, for preventing and controlling… (2019) · Cochrane
MD -0.01 [-0.19, 0.21]1 study · 12 participantsVery low
Oral hygiene care training of carers vs No training (or a placebo training session) of carers
Gingival inflammation (medium term) · People with mixed levels of ID (age range unclear); setting residential · Medium term (6 weeks to 12 months)
Oral hygiene interventions for people with intellectual disabilities (2019) · Cochrane
MD -0.09 [-0.63, 0.45]2 studies · 99 participantsLow
Daily toothbrushing by a dental student vs Twice-weekly or once-weekly toothbrushing by a dental student
Gingival inflammation (short term) · People aged 15 to 30 years with mixed levels of ID; setting residential · Short term (<6 weeks)
Oral hygiene interventions for people with intellectual disabilities (2019) · Cochrane
Daily vs twice-weekly or once-weekly toothbrushing by dental students. Buccal and labial Loe & Silness index, mean 21 days; 80 participants (1 RCT); Low. Brushing daily most likely reduced gingival inflammation more…1 study · 80 participantsLow
Special manual toothbrush (self, carer or carer-assisted brushing) vs Conventional manual toothbrush (self, carer or carer-assisted brushing)
Gingival inflammation (medium term) · Children and adults with mixed levels of ID; setting home, residential, day care, school, mixed or not specified · Medium term (6 weeks to 12 months)
Oral hygiene interventions for people with intellectual disabilities (2019) · Cochrane
MD -12.40 [-24.31, -0.49]1 study · 18 participantsVery low
Wooden cleaning stick plus toothbrushing vs Flossing plus toothbrushing
Gingivitis (proportion of bleeding sites) · Adults, 16 years and older (dentate) · 3 months
Home use of interdental cleaning devices, in addition to toothbrushing, for preventing and controlling… (2019) · Cochrane
MD 0.01 [-0.12, 0.14]1 study · 24 participantsVery low
Rubber/elastomeric cleaning stick plus toothbrushing vs Flossing plus toothbrushing
Gingivitis (proportion of bleeding sites) · Adults, 16 years and older (dentate) · 1 month
Home use of interdental cleaning devices, in addition to toothbrushing, for preventing and controlling… (2019) · Cochrane
MD -0.03 [-0.08, 0.03]5 studies · 212 participantsLow
Any form of one-to-one oral hygiene advice (OHA) vs No OHA
Periodontal health: gingivitis · Children or adults (fit and healthy, or with a well-defined medical condition) · 3 to 36 months
One‐to‐one oral hygiene advice provided in a dental setting for oral health (2018) · Cochrane
SoF: 1 small study in adults had contradictory results at 3 and 6 months; the other study in adults showed evidence of a benefit for OHA at all time points (12, 24, 36 months). Results: Hetland 1982 MD 0.25 (0.05 to…2 studies · 235 participantsVery low
Any form of one-to-one oral hygiene advice (OHA) vs No OHA
Periodontal health: plaque levels · Children or adults (fit and healthy, or with a well-defined medical condition) · 6 to 36 months
One‐to‐one oral hygiene advice provided in a dental setting for oral health (2018) · Cochrane
SoF: Both studies at all time points consistently showed a benefit in plaque reduction for OHA. Results: Hetland 1982 MD -0.41 (-0.54 to -0.28) at 3mo, -0.44 (-0.56 to -0.32) at 6mo; Hugoson 2007 MD -13.00 (-19.89 to…2 studies · 235 participantsLow
Educational intervention with information and practical components (theoretical oral health education plus practical skills training) for nursing staff and/or residents vs (Optimised) usual care
Gingivitis · Nursing home residents (mean age 78.3 to 86.0 years; more than 66% women; 62.1% to 87.3% with dental prostheses) · 3 to 6 months
Oral health educational interventions for nursing home staff and residents (2016) · Cochrane
SoF: Gingivitis (Gingival Bleeding Index and method of Suomi; follow-up 3 to 6 months). No meta-analysis (data not comparable). 245 participants (3 RCTs); low quality. Comment: 3 studies at unclear risk of bias showed…3 studies · 245 participantsLow
Interdental brushing plus toothbrushing vs Flossing plus toothbrushing
Gingivitis (bleeding and gingival indices; standardised across indices) · Dentate adults aged 16 years and older · 1 month (4 to 6 weeks)
Interdental brushing for the prevention and control of periodontal diseases and dental caries in adults (2013) · Cochrane
SMD -0.53 [-0.81, -0.24]7 studies · 326 participantsLow
Interdental brushing plus toothbrushing vs Flossing plus toothbrushing
Gingivitis (bleeding and gingival indices; standardised across indices) · Dentate adults aged 16 years and older · 3 months (12 weeks)
Interdental brushing for the prevention and control of periodontal diseases and dental caries in adults (2013) · Cochrane
SMD -1.98 [-5.42, 1.47]2 studies · 107 participantsVery low
Interdental brushing plus toothbrushing vs Toothbrushing alone
Gingivitis (Loe-Silness gingival index, interproximal; scale 0 to 4) · Dentate adults aged 16 years and older · 4 weeks (1 month)
Interdental brushing for the prevention and control of periodontal diseases and dental caries in adults (2013) · Cochrane
MD -0.53 [-0.83, -0.23]1 study · 62 participantsVery low
Flossing plus toothbrushing (self-performed; manual or automated floss) vs Toothbrushing alone (with or without a negative-control/placebo rinse)
Gingivitis (Gingival Index, 0-3 scale; SMD) · Dentate adults aged 16 years or older (excluding orthodontic patients and those with severe periodontal disease) · 3 months
Flossing for the management of periodontal diseases and dental caries in adults (2011) · Cochrane
SMD -0.41 [-0.68, -0.14]6 studies · 656 participantsUngraded
Flossing plus toothbrushing (self-performed; manual or automated floss) vs Toothbrushing alone (with or without a negative-control/placebo rinse)
Gingivitis (Loe-Silness/bleeding indices; SMD) · Dentate adults aged 16 years or older (excluding orthodontic patients and those with severe periodontal disease) · 1 month
Flossing for the management of periodontal diseases and dental caries in adults (2011) · Cochrane
SMD -0.36 [-0.66, -0.05]7 studies · 489 participantsVery low
Flossing plus toothbrushing (self-performed; manual or automated floss) vs Toothbrushing alone (with or without a negative-control/placebo rinse)
Gingivitis (Gingival Index, 0-3 scale; SMD) · Dentate adults aged 16 years or older (excluding orthodontic patients and those with severe periodontal disease) · 6 months
Flossing for the management of periodontal diseases and dental caries in adults (2011) · Cochrane
SMD -0.72 [-1.09, -0.35]4 studies · 564 participantsUngraded
Psychological intervention based on a specified psychological model/theory (to increase adherence to oral hygiene instructions) vs No (active) intervention (usual/standard dental care or no-treatment control)
Gingival bleeding · Adults (aged 18 or over) diagnosed with periodontal disease (gingivitis or periodontitis) · 4 months
Psychological interventions to improve adherence to oral hygiene instructions in adults with periodontal… (2007) · Cochrane
Little 1997 reported decreased gingival bleeding in the active intervention group: gingival bleeding present in 9% of the intervention group at baseline and 4% at 4-month follow up, versus 10% of the control group on…1 study · 107 participantsUngraded

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