Same question across reviews · CL0205

intervention :: Nutritional supplement -> White-spot/initial lesions

ProposalThis cluster groups questions by review type, intervention category and outcome domain. It is a proposal pending human validation, so questions in it may differ in population, comparator or timing.
Reviews
1
Questions
1
current versions
GRADE rated
0
Review overlap (CCA)
NR
over all included studies of these reviews, not this question only
QuestionEffectEvidenceStatus / GRADE
Calcium fluoride nanoparticle (nCaF2)-containing orthodontic primer vs Conventional primer (Transbond)
Enamel demineralization / white spot lesions (DIAGNOdent, photographic scoring) · Patients undergoing fixed orthodontic (fixed appliance) treatment (adolescents and adults, ages 12 to 35) · 1, 3 and 6 months (during treatment to debonding)
Can Orthodontic Adhesive Systems Inhibit the Formation and Development of White Spot Lesions During Fixed… (2024)
Al Tuma 2023 (1 split-mouth RCT, 31 patients / 310 teeth): DIAGNOdent scores significantly favored the nCaF2 primer at 1, 3 and 6 months (p=0.000) and S. mutans count differed at 1 month; no significant difference in…1 study · 31 participantsUngraded

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