Same question across reviews · CL0180

intervention :: Glass ionomer / ART -> White-spot/initial lesions

ProposalThis cluster groups questions by review type, intervention category and outcome domain. It is a proposal pending human validation, so questions in it may differ in population, comparator or timing.
Reviews
3
Questions
5
current versions
GRADE rated
2
Review overlap (CCA)
0.029
over all included studies of these reviews, not this question only
QuestionEffectEvidenceStatus / GRADE
Resin-modified glass-ionomer cement (RM-GIC) for bracket bonding vs Conventional composite resin adhesive (Transbond XT)
New white spot lesion incidence (and first-time bracket bond failure) · Patients undergoing fixed orthodontic (fixed appliance) treatment (adolescents and adults, ages 12 to 35) · During fixed appliance treatment
Can Orthodontic Adhesive Systems Inhibit the Formation and Development of White Spot Lesions During Fixed… (2024)
Benson 2019 (1 multicenter single-blind RCT, 197 patients): no difference in the proportion of patients with new WSLs or first-time bracket failures between RM-GIC and resin adhesive (p>0.05). No meta-analysis performed.1 study · 197 participantsUngraded
Fluoride-releasing glass ionomer-based bonding agent vs Non-fluoride glass ionomer-based bonding agent
Initiation of white spot lesions (WSL), visual-tactile assessment · Patients of any age (11-40 years) receiving comprehensive/fixed orthodontic treatment with fixed appliances · 1-24 months follow-up, Glass ionomer-based bonding agent
Efficacy of sealants and bonding materials during fixed orthodontic treatment to prevent enamel… (2021)
RR 0.64 [0.41, 0.99]1 study · 144 participantsUngraded
Glass ionomer cement vs Resin adhesive
Incidence of new white spot lesions by visual-tactile assessment · Patients receiving comprehensive fixed orthodontic treatment · 12 to 24 months, Overall
Efficacy of sealants and bonding materials during fixed orthodontic treatment to prevent enamel… (2021)
RR 0.72 [0.34, 1.54]3 studies · 394 participantsVery low
Glass ionomer cement (for bracket bonding) vs Resin adhesive (for bracket bonding)
Initiation of white spot lesions (WSL), visual-tactile assessment · Patients of any age (11-40 years) receiving comprehensive/fixed orthodontic treatment with fixed appliances · 12-24 months follow-up
Efficacy of sealants and bonding materials during fixed orthodontic treatment to prevent enamel… (2021)
RR 0.72 [0.34, 1.54]3 studies · 394 participantsVery low
Chemically cured glass ionomer cement vs Light-cured compomer (polyacid-modified composite resin)
Decalcification (enamel white spot lesions) · Patients with full arch fixed orthodontic appliances with bands attached to molars (patients with cleft lip/palate or… · Approximately 12 months (to end of treatment)
Adhesives for fixed orthodontic bands (2016) · Cochrane
Gillgrass 2001 (98 participants): comparison of change in mean enamel white spot lesion scores during treatment showed no statistically significant difference between chemically cured glass ionomer and light-cured…1 study · 98 participantsUngraded

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