Same question across reviews · CL0170
intervention :: Fluoride varnish -> White-spot/initial lesions
ProposalThis cluster groups questions by review type, intervention category and outcome domain. It is a proposal pending human validation, so questions in it may differ in population, comparator or timing.
Reviews
1
Questions
2
current versions
GRADE rated
1
Review overlap (CCA)
NR
over all included studies of these reviews, not this question only
| Question | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Fluoride varnish applied periodically (at least quarterly) around the bracket bases during treatment vs Placebo varnish, resin sealant, or standard care (oral hygiene instructions) Prevalence of white spot lesions (WSL) at debonding, subject level · Healthy adolescents and adults undergoing orthodontic treatment with fixed multi-bracket appliances · At debonding Prevention of white spot lesions with fluoride varnish during orthodontic treatment with fixed appliances: a… (2023) | RR 0.64 [0.42, 0.98] | 5 studies · 558 participants | Very low |
Fluoride varnish applied periodically (at least quarterly) around the bracket bases during treatment vs Placebo varnish, resin sealant, or standard care (oral hygiene instructions) White spot lesion clinical score (mean values), subject level · Healthy adolescents and adults undergoing orthodontic treatment with fixed multi-bracket appliances · At debonding Prevention of white spot lesions with fluoride varnish during orthodontic treatment with fixed appliances: a… (2023) | SMD -0.44 [-0.64, -0.24] | 2 studies · 258 participants | Ungraded |