Same question across reviews · CL0128
intervention :: Fluoride gel/foam -> Caries increment (DMFS/DMFT)
ProposalThis cluster groups questions by review type, intervention category and outcome domain. It is a proposal pending human validation, so questions in it may differ in population, comparator or timing.
Reviews
3
Questions
13
current versions
GRADE rated
2
Review overlap (CCA)
NR
over all included studies of these reviews, not this question only
| Question | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Fluoride gel (topically applied; operator- or self-applied; any fluoride agent/concentration; frequency at least once a year) vs Placebo or no treatment Caries increment on permanent whole teeth (D(M)FT), prevented fraction · Children and adolescents aged 16 years or younger (permanent dentition) · Nearest to 3 years Fluoride gels for preventing dental caries in children and adolescents (2015) · Cochrane | PF 0.32 [0.19, 0.46] | 10 studies | Ungraded |
Fluoride gel (topically applied; operator- or self-applied; any fluoride agent/concentration; frequency at least once a year) vs Placebo or no treatment Caries increment on permanent tooth surfaces (D(M)FS), prevented fraction · Children and adolescents aged 16 years or younger (permanent dentition) · Nearest to 3 years, Placebo-controlled trials Fluoride gels for preventing dental caries in children and adolescents (2015) · Cochrane | PF 0.21 [0.15, 0.28] | 15 studies · 5671 participants | Ungraded |
Fluoride gel (topically applied; operator- or self-applied; any fluoride agent/concentration; frequency at least once a year) vs Placebo or no treatment Caries increment on permanent whole teeth (D(M)FT), prevented fraction · Children and adolescents aged 16 years or younger (permanent dentition) · Nearest to 3 years, Placebo-controlled trials Fluoride gels for preventing dental caries in children and adolescents (2015) · Cochrane | PF 0.18 [0.09, 0.27] | 4 studies | Ungraded |
Fluoride gel (topically applied; operator- or self-applied; any fluoride agent/concentration; frequency at least once a year) vs Placebo or no treatment Caries increment on primary (deciduous) tooth surfaces (d(e/m)fs), prevented fraction · Children with primary (deciduous) teeth (mostly preschool children aged under 6 years) · Nearest to 3 years Fluoride gels for preventing dental caries in children and adolescents (2015) · Cochrane | PF 0.20 [0.01, 0.38] | 3 studies · 1254 participants | Low |
Fluoride gel (topically applied; operator- or self-applied; any fluoride agent/concentration; frequency at least once a year) vs Placebo or no treatment Caries increment on permanent tooth surfaces (D(M)FS), prevented fraction · Children and adolescents aged 16 years or younger (permanent dentition) · Nearest to 3 years, No-treatment-controlled trials Fluoride gels for preventing dental caries in children and adolescents (2015) · Cochrane | PF 0.38 [0.24, 0.52] | 10 studies · 2808 participants | Ungraded |
Fluoride gel (topically applied; operator- or self-applied; any fluoride agent/concentration; frequency at least once a year) vs Placebo or no treatment Caries increment on permanent tooth surfaces (D(M)FS), prevented fraction · Children and adolescents aged 16 years or younger (permanent dentition) · Nearest to 3 years Fluoride gels for preventing dental caries in children and adolescents (2015) · Cochrane | PF 0.28 [0.19, 0.36] | 25 studies · 8479 participants | Moderate |
Fluoride gel (topically applied; operator- or self-applied; any fluoride agent/concentration; frequency at least once a year) vs Placebo or no treatment Caries increment on permanent whole teeth (D(M)FT), prevented fraction · Children and adolescents aged 16 years or younger (permanent dentition) · Nearest to 3 years, No-treatment-controlled trials Fluoride gels for preventing dental caries in children and adolescents (2015) · Cochrane | PF 0.43 [0.29, 0.57] | 6 studies | Ungraded |
Fluoride gel (topically applied; operator- or self-applied; any fluoride agent/concentration; frequency at least once a year) vs Placebo or no treatment Caries increment on primary (deciduous) whole teeth (d(m)ft), prevented fraction · Children with primary (deciduous) teeth (mostly preschool children aged under 6 years) · Nearest to 3 years Fluoride gels for preventing dental caries in children and adolescents (2015) · Cochrane | There were no data on d(m)ft available. | 0 studies | No studies |
Fluoride gel combined with fluoride mouthrinse vs Fluoride gel alone Caries increment in permanent teeth: D(M)FS (prevented fraction) · Children or adolescents aged 16 years or less · Nearest to 3 years Combinations of topical fluoride (toothpastes, mouthrinses, gels, varnishes) versus single topical fluoride… (2004) · Cochrane | PF 0.23 [0.04, 0.43] | 2 studies · 497 participants | Ungraded |
Fluoride mouthrinse combined with fluoride gel vs Fluoride mouthrinse alone Caries increment in permanent teeth: D(M)FS (prevented fraction) · Children or adolescents aged 16 years or less · Nearest to 3 years Combinations of topical fluoride (toothpastes, mouthrinses, gels, varnishes) versus single topical fluoride… (2004) · Cochrane | PF 0.02 [-0.20, 0.24] | 1 study · 252 participants | Ungraded |
Fluoride gel vs Fluoride mouthrinse Caries increment (D(M)FS), permanent teeth · Children or adolescents aged 16 or less at the start of the study · 1 to 3 years (final follow-up) One topical fluoride (toothpastes, or mouthrinses, or gels, or varnishes) versus another for preventing… (2004) · Cochrane | PF -0.14 [-0.40, 0.12] | 1 study · 257 participants | Ungraded |
Fluoride gel combined with fluoride toothpaste vs Fluoride gel alone Caries increment in permanent teeth: D(M)FS (prevented fraction) · Children or adolescents aged 16 years or less · Nearest to 3 years Combinations of topical fluoride (toothpastes, mouthrinses, gels, varnishes) versus single topical fluoride… (2004) · Cochrane | PF 0.10 [-0.01, 0.21] | 3 studies · 759 participants | Ungraded |
Fluoride gel combined with fluoride toothpaste vs Fluoride toothpaste alone Caries increment in permanent teeth: D(M)FS (prevented fraction) · Children or adolescents aged 16 years or less · Nearest to 3 years Combinations of topical fluoride (toothpastes, mouthrinses, gels, varnishes) versus single topical fluoride… (2004) · Cochrane | PF 0.14 [-0.09, 0.38] | 3 studies · 1217 participants | Ungraded |