Same question across reviews · CL0117
intervention :: Exposure: microbial -> Adverse effects/fluorosis
ProposalThis cluster groups questions by review type, intervention category and outcome domain. It is a proposal pending human validation, so questions in it may differ in population, comparator or timing.
Reviews
1
Questions
3
current versions
GRADE rated
1
Review overlap (CCA)
NR
over all included studies of these reviews, not this question only
| Question | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Botulinum toxin (BoNT) injection into salivary glands vs Placebo injection Adverse events (participants with >=1 adverse event) · Adults with Parkinson's disease and sialorrhea (drooling) · Approximately 1 month post-injection (one study ~1 week), BoNT type A The effectiveness and safety of botulinum toxin injections for the treatment of sialorrhea with Parkinson's… (2023) | RD 0.10 [0.00, 0.21] | 5 studies · 117 participants | Ungraded |
Botulinum toxin (BoNT) injection into salivary glands vs Placebo injection Adverse events (participants with >=1 adverse event) · Adults with Parkinson's disease and sialorrhea (drooling) · Approximately 1 month post-injection (one study ~1 week) The effectiveness and safety of botulinum toxin injections for the treatment of sialorrhea with Parkinson's… (2023) | RD 0.15 [0.05, 0.24] | 10 studies · 249 participants | Low |
Botulinum toxin (BoNT) injection into salivary glands vs Placebo injection Adverse events (participants with >=1 adverse event) · Adults with Parkinson's disease and sialorrhea (drooling) · Approximately 1 month post-injection (one study ~1 week), BoNT type B The effectiveness and safety of botulinum toxin injections for the treatment of sialorrhea with Parkinson's… (2023) | RD 0.18 [0.04, 0.33] | 5 studies · 132 participants | Ungraded |