Same question across reviews · CL0084
intervention :: Antimicrobial (other) -> Adverse effects/fluorosis
ProposalThis cluster groups questions by review type, intervention category and outcome domain. It is a proposal pending human validation, so questions in it may differ in population, comparator or timing.
Reviews
3
Questions
4
current versions
GRADE rated
1
Review overlap (CCA)
NR
over all included studies of these reviews, not this question only
| Question | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Full-mouth scaling (FMS): scaling/root planing (subgingival instrumentation) of all quadrants within 24 hours, without antiseptic vs Quadrant scaling and root planing (control): SRP of each quadrant in separate sessions at least one week apart Adverse events · Adults with a clinical diagnosis of (chronic) periodontitis (1999 classification); studies of aggressive… Full‐mouth treatment modalities (within 24 hours) for periodontitis in adults (2022) · Cochrane | 13 studies provided adverse-event/participant-reported information; 3 reported an event after FMD or FMS; most important harm was increased body temperature after treatment. Narrative, not separated by comparison and… | 13 studies | Ungraded |
Toothbrushing (with or without antiseptics), as part of oral hygiene care vs No toothbrushing (with or without antiseptics) Adverse effects · Critically ill adults receiving mechanical ventilation in ICU Oral hygiene care for critically ill patients to prevent ventilator‐associated pneumonia (2020) · Cochrane | Adverse effects: information from two studies, which stated that there were none; very low certainty. There is a lack of evidence about adverse effects. | 2 studies | Very low |
Povidone iodine rinse vs Saline rinse or placebo Adverse effects · Critically ill patients receiving mechanical ventilation in ICU Oral hygiene care for critically ill patients to prevent ventilator‐associated pneumonia (2020) · Cochrane | Adverse effects (Seguin 2014): no evidence of a difference in acute respiratory distress syndrome (RR 11.00, 95% CI 0.62 to 195.61), agitation and/or hypertension (RR 0.48, 95% CI 0.12 to 1.86), epistaxis (RR 0.14, 95%… | 1 study | Ungraded |
Periodontal treatment (scaling and root planing, polishing, or surgery), alone or with oral hygiene counselling, antiseptics, or antimicrobials vs No treatment Adverse effects of therapy · Pregnant women considered to have periodontal disease (gingivitis or periodontitis) after dental examination Treating periodontal disease for preventing adverse birth outcomes in pregnant women (2017) · Cochrane | 0% in both groups; Not estimated; 2389 participants (4 RCTs) | 4 studies · 2389 participants | Ungraded |