Same question across reviews · CL0080
DTA :: Exposure: microbial -> Diagnostic accuracy
ProposalThis cluster groups questions by review type, intervention category and outcome domain. It is a proposal pending human validation, so questions in it may differ in population, comparator or timing.
Reviews
1
Questions
4
current versions
GRADE rated
0
Review overlap (CCA)
NR
over all included studies of these reviews, not this question only
| Question | Effect | Evidence | Status / GRADE |
|---|---|---|---|
COE with blood/salivary (biomarker) analysis vs Reference standard: examination and clinical evaluation by a physician/clinician with specialist knowledge or training (long-term follow-up accepted for those screened negative) Outcome NR · Apparently healthy adults not reporting symptoms of OPMD or OSCC, attending an organised screening or surveillance… Clinical assessment for the detection of oral cavity cancer and potentially malignant disorders in… (2021) · Cochrane | There were no eligible studies evaluating blood or salivary sample analysis (which tests for the presence of biomarkers for OPMD and OSCC). | 0 studies | No studies |
COE with blood/salivary (biomarker) analysis vs COE with vital rinsing (toluidine blue/tolonium chloride) Outcome NR · Apparently healthy adults not reporting symptoms of OPMD or OSCC, attending an organised screening or surveillance… Clinical assessment for the detection of oral cavity cancer and potentially malignant disorders in… (2021) · Cochrane | No eligible studies; planned comparative analysis (COE with vital rinse vs COE with blood/salivary analysis) not populated in this version. | 0 studies | No studies |
COE with blood/salivary (biomarker) analysis vs Conventional oral examination (COE) alone Outcome NR · Apparently healthy adults not reporting symptoms of OPMD or OSCC, attending an organised screening or surveillance… Clinical assessment for the detection of oral cavity cancer and potentially malignant disorders in… (2021) · Cochrane | No eligible studies; planned comparative analysis (COE vs COE with blood/salivary analysis) not populated in this version. | 0 studies | No studies |
COE with blood/salivary (biomarker) analysis vs COE with light-based detection (e.g. ViziLite Plus, Microlux/DL, VELscope, Identafi 3000) Outcome NR · Apparently healthy adults not reporting symptoms of OPMD or OSCC, attending an organised screening or surveillance… Clinical assessment for the detection of oral cavity cancer and potentially malignant disorders in… (2021) · Cochrane | No eligible studies; planned comparative analysis (COE with light-based detection vs COE with blood/salivary analysis) not populated in this version. | 0 studies | No studies |